Ready Stock Intermediate 388082
Ready stock intermediate 388082-77-7 99.8% Lapatinib DitosylateLapatinib DitosylateCAS Number: 388082-77-7Molecular form
Basic Info.
Model NO. | Lapatinib Ditosylate Powder |
Usage | Pharm |
Raw Material | 388082-77-7 |
Transport Machine | Ordinary Goods Truck |
Heavy Metals | Nmt 20ppm |
Total Impurities | Nmt 1.0% |
Appearance | Yellow Powder |
Loss on Drying | Nmt 1.5% |
Transport Package | Drum |
Specification | 99% |
Trademark | Recedar |
Origin | China |
HS Code | 0000 |
Production Capacity | 1000kg |
Product Description
Ready stock intermediate 388082-77-7 99.8% Lapatinib DitosylateLapatinib DitosylateCAS Number: 388082-77-7Molecular formula: C43H42ClFN4O10S3Molecular weight: 925.46EINECS number: 1312995-182-4Appearance: yellow powderPurity: 99%High quality 99.8% Lapatinib Ditosylate powder with CAS 388082-77-7 Lapatinib (GW-572016) Ditosylate is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM in the cell-free assay, respectively.ResearchLapatinib was administered orally at a dose of ~100mg/kg, twice a day, and significantly inhibited the growth of BT474 and HN5 xenograft tumors. This effect was dose-dependent in Chemicalbook. Consistent with in vitro activity, Lapatinib treated mice bearing H1975 tumors at a dose of 100-150 mg/kg to delay tumor growth.
Package | carton drum with two plastic bags inside |
Net weight | 25KG/Drum |
Storage | Sealed in cool and dry place to avoid moisture and light |
Shelf life | 2 years when properly stored |
Lead time | 1~3 days after confirmation |
Test Items | Test Standards |
Description | Yellow powder |
Total impurities | ≤1.0% |
Heavy metals | ≤20ppm |
Water content | 0.5%~1.2% |
Purity | ≥99.0% |
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